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Nucleoside Reverse Transcriptase Inhibitors [MoA]

Known as: Nucleoside Reverse Transcriptase Inhibitors 
National Institutes of Health

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22 relations
DidanosineHepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Lamivudine

Papers overview

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2017
2017
Week 96 efficacy and safety of darunavir/ritonavir monotherapy vs. darunavir/ritonavir with two nucleoside reverse transcriptase inhibitors in the PROTEA trial
PROTEA is a randomized controlled trial to assess the efficacy and safety of darunavir/ritonavir (DRV/r) monotherapy as an… 
2014
2014
Successful treatment of l-asparaginase-induced severe acute hepatotoxicity using mitochondrial cofactors
l-asparaginase (L-ase) is a major drug used to treat acute lymphoblastic leukemia (ALL) [1]. L-ase kills leukemic cells by… 
2014
2014
The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy
2009
2009
High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.
OBJECTIVES To determine the rates, reasons and predictors of treatment change of the initial antiretroviral treatment (ART… 
2009
2009
Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study.
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) used for the treatment of HIV-1 inhibit the replication of mitochondrial DNA… 
2005
2005
3′-Azido-2′,3′-Dideoxythymidine (Zidovudine) Uptake Mechanisms in T Lymphocytes
The nucleoside reverse transcriptase inhibitors (NRTIs) make up a family of antiretroviral drugs widely used in the treatment of… 
2003
2003
HIV-1 Resistance Profile of the Novel Nucleoside Reverse Transcriptase Inhibitor β-D-2′,3′-Dideoxy-2′,3′-Didehydro-5-Fluorocytidine (Reverset™)
Nucleoside reverse transcriptase inhibitors (NRTIs) represent the cornerstone of highly active antiretroviral therapy when… 
2002
2002
Prevalence of the mutational pattern E44D/A and/or V118I in the reverse transcriptase (RT) gene of HIV‐1 in relation to treatment with nucleoside analogue RT inhibitors
It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIV‐1… 
2001
2001
Hyperlactataemia in HIV-Infected Patients: The Role of NRTI-Treatment
Background Long-term treatment with nucleoside reverse transcriptase inhibitors (NRTIs) can induce mitochondrial dysfunction… 
2000
2000
Different immunologic profiles characterize HIV infection in highly active antiretroviral therapy-treated and antiretroviral-naïve patients with undetectable viraemia
BackgroundSuppression of human immunodeficiency virus (HIV) replication can be obtained in chronically infected individuals by… 
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